Phuongly Pham

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Ingrid Choong, Willard Lew, Dennis Lee et al. · Journal of Medicinal Chemistry · 2002 · 105 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Fragment-Based Discovery of Nonpeptidic BACE-1 Inhibitors Using Tethering

Wenjin Yang, Raymond V. Fucini, Bruce J. Fahr et al. · Biochemistry · 2009 · 49 citations

Life Sciences, Biochemistry, Medicinal Chemistry +17

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Raymond V. Fucini, Emily J. Hanan, M.J. Romanowski et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Tethering identifies fragment that yields potent inhibitors of human caspase-1

Bruce J. Fahr, Phuongly Pham, Nathan D. Waal et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 27 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +11

Identification of potent and novel small-Molecule inhibitors of caspase-3

Darin A. Allen, Phuongly Pham, Ingrid Choong et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 27 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +12