Nathan D. Waal

Discovery of a Potent Small Molecule IL-2 Inhibitor through Fragment Assembly

Andrew C. Braisted, Johan D. Oslob, Warren L. DeLano et al. · Journal of the American Chemical Society · 2003 · 249 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2:  An Approach for Inhibiting Protein−Protein Interactions

Brian C. Raimundo, Johan D. Oslob, Andrew C. Braisted et al. · Journal of Medicinal Chemistry · 2004 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon et al. · Journal of Medicinal Chemistry · 2014 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Tethering identifies fragment that yields potent inhibitors of human caspase-1

Bruce J. Fahr, Phuongly Pham, Nathan D. Waal et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 27 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +11

Structural analysis of caspase-1 inhibitors derived from Tethering

Bruce J. Fahr, Michelle M. Sopko, Joni W. Lam et al. · Acta Crystallographica Section F Structural Biology and Crystallization Communications · 2005 · 25 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +16