Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays

Michael J. Kozal, Nila Shah, Naiping Shen, +8

Nature Medicine

Human RetrovirusGeneticsGenetic EpidemiologyHuman PolymorphismMolecular Biology +9

Cystic fibrosis mutation detection by hybridization to light-generated DNA probe arrays

Maureen Cronin, Raymond V. Fucini, Soo Mee Kim, +3

Human Mutation

EngineeringGeneticsDna AnalysisMolecular BiologyNucleic Acid Amplification Test +16

Golgi Vesicle Proteins Are Linked to the Assembly of an Actin Complex Defined by mAbp1

Raymond V. Fucini, Ji‐Long Chen, Catherine G.N. Sharma, +2

Molecular Biology of the Cell

Molecular BiologyCytoskeletonCellular PhysiologyAutophagyActin Complex +14

Osmotic Shock Inhibits Insulin Signaling by Maintaining Akt/Protein Kinase B in an Inactive Dephosphorylated State

Dong Chen, Raymond V. Fucini, Ann Louise Olson, +2

Molecular and Cellular Biology

Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles

Ji‐Long Chen, Raymond V. Fucini, Lynne Lacomis, +3

The Journal of Cell Biology

Activated ADP-ribosylation Factor Assembles Distinct Pools of Actin on Golgi Membranes

Raymond V. Fucini, Araceli Navarrete, Catherine Vadakkan, +4

Journal of Biological Chemistry

Proteinlipid InteractionActin PoolMolecular BiologyCytoskeletonArf-dependent Actin Pool +14

The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model

Erica C. VanderPorten, Pietro Taverna, Jennifer N. Hogan, +3

Molecular Cancer Therapeutics

Cell CultureCancer BiologyTumor BiologyReceptor Tyrosine KinaseColon Carcinoma Model +16

Nucleobase and Ribose Modifications Control Immunostimulation by a MicroRNA-122-mimetic RNA

Hayden Peacock, Raymond V. Fucini, Prasanna Jayalath, +5

Journal of the American Chemical Society

EngineeringImmunologyMolecular BiologyTherapeuticsImmunotherapy +15

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo

Jennifer P. Arbitrario, Brian J. Belmont, Marc Evanchik, +17

Cancer Chemotherapy and Pharmacology

Potent Anti-tumor ActivityNovel TherapyMedicineReceptor Tyrosine KinaseImmune Checkpoint Inhibitor +8

Aminoethylenes:  A Tetrahedral Intermediate Isostere Yielding Potent Inhibitors of the Aspartyl Protease BACE-1

Wenjin Yang, Wanli Lu, Yafan Lu, +12

Journal of Medicinal Chemistry