Michael Rooney - Concepedia

Author

Michael Rooney

Also Known As

M. ROONEY, M. Rooney, M.M. Rooney, M.T. Rooney, Michael Rooney, Michael T. Rooney, Michael T. V. Rooney, Michael T.V Rooney

Publications

490

Citations

H-Index

Concepts

All Affiliations

AstraZeneca (United States)Biogen (United States)University of New Hampshire

About

Michael Rooney is an author at AstraZeneca (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	279
2	Natural Sciences	4	4	100
3	Biochemistry	4	4	100
4	Engineering	3	3	84
5	Health Sciences	1	1	76

Michael Rooney

Publications

463

Citations

H-Index

Page 1

	Year	Citations
Discovery of a Novel Class of Dimeric Smac Mimetics as Potent IAP Antagonists Resulting in a Clinical Candidate for the Treatment of Cancer (AZD5582) Edward J. Hennessy, Ammar Adam, Brian Aquila, Journal of Medicinal Chemistry Compound 14ApoptosisCell DeathPharmacotherapyTumor Biology	2013	112
Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy Aryun Kim, Amy Kutschke, David E. Ehmann, Antimicrobial Agents and Chemotherapy Microbial PathogensAntimicrobial ChemotherapyAdaptive ResistanceAntibiotic ResistanceBacterial Pathogens	2015	76
Hybridization Liquid Chromatography–Tandem Mass Spectrometry: An Alternative Bioanalytical Method for Antisense Oligonucleotide Quantitation in Plasma and Tissue Samples Pei Li, Yuqing Gong, Jaeah Kim, Analytical Chemistry	2020	59
Derivatized, swellable polymer microspheres for chemical transduction W. Rudolf Seitz, Michael Rooney, Eric William Miele, Analytica Chimica Acta Swellable Polymer MicrospheresEngineeringSmart PolymerPolymer ScienceMicro-encapsulation	1999	38
An optically sensitive membrane for pH based on swellable polymer microspheres in a hydrogel Michael Rooney, W. Rudolf Seitz Analytical Communications EngineeringSmart PolymerPolymer NanotechnologyResponsive PolymersBiomedical Engineering	1999	33
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo Tamara Halkina, Jaclyn L. Henderson, Edward Yin-Shiang Lin, Journal of Medicinal Chemistry	2021	32
SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of <i>Pseudomonas aeruginosa</i> PBP3 Kerry E. Murphy-Benenato, Brian Dangel, Hajnalka E. Davis, ACS Medicinal Chemistry Letters New AgentsTarget PenicillinAntimicrobial ChemotherapyAnalytical UltracentrifugationChemical Biology	2015	27
Discovery of Efficacious <i>Pseudomonas aeruginosa</i>-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model Kerry E. Murphy-Benenato, Pratik Bhagunde, April Chen, Journal of Medicinal Chemistry Lead CompoundsNew AgentsAntimicrobial ChemotherapyPharmacodynamic ModelingDrug Resistance	2015	26
Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity Edward J. Hennessy, Vibha Oza, Ammar Adam, Journal of Medicinal Chemistry Pharmaceutical ScienceDrug TargetHigh ThroughputPharmacotherapyChemical Biology	2015	25
Discovery of bacterial NAD+-dependent DNA ligase inhibitors: Improvements in clearance of adenosine series S. Stokes, Madhusudhan Gowravaram, Hoan K. Huynh, Bioorganic & Medicinal Chemistry Letters Cellular EnzymologyAdenosine SeriesBiochemistryNatural SciencesOligonucleotide	2011	22

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