Matthew C. Lucas

Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity

Benjamin Vincent, Daniel F. Tardiff, Jeff S. Piotrowski et al. · Cell Reports · 2018 · 130 citations · Full text

Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition

Brian S. Safina, Stewart Baker, Matt Baumgardner et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Drug Target, Immunology, Inflammatory Arthritis +25

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Jeremy Murray, Zachary K. Sweeney, Bryan Chan et al. · Journal of Medicinal Chemistry · 2012 · 65 citations · Full text

Medicinal Chemistry, Drug Target, Pharmaceutical Chemistry +15

The synthesis of a natural product family: from debromoisolaurinterol to the aplysins

Matthew C. Lucas, Peter D. Howes · Tetrahedron · 2001 · 55 citations

Biosynthesis, Engineering, Natural Product Synthesis +5

Discovery of Highly Selective and Orally Active Lysophosphatidic Acid Receptor-1 Antagonists with Potent Activity on Human Lung Fibroblasts

Yimin Qian, Matthew J. Hamilton, Achyutharao Sidduri et al. · Journal of Medicinal Chemistry · 2012 · 54 citations · Full text

Immunology, Pharmacotherapy, Lpa Stimulation +20