Daniel F. Tardiff

Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons

Chee Yeun Chung, Vikram Khurana, Pavan K. Auluck et al. · Science · 2013 · 455 citations · Full text

Neurogenomics, Genetics, Neurochemical Biomarkers +24

Yeast Reveal a “Druggable” Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons

Daniel F. Tardiff, Nathan T. Jui, Vikram Khurana et al. · Science · 2013 · 251 citations · Full text

Molecular Biology, Synaptic Signaling, Yeast Reveal +20

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models

Linhui Julie Su, Pavan K. Auluck, Tiago F. Outeiro et al. · Disease Models & Mechanisms · 2009 · 175 citations · Full text

Er-to-golgi Trafficking Defects, Mitophagy, Mitochondrial Dysfunction +23

Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity

Kent Matlack, Daniel F. Tardiff, Priyanka Narayan et al. · Proceedings of the National Academy of Sciences · 2014 · 165 citations · Full text

Unbiased Screen, Neurochemical Biomarkers, Peptide Science +18

Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity

Benjamin Vincent, Daniel F. Tardiff, Jeff S. Piotrowski et al. · Cell Reports · 2018 · 130 citations · Full text