Peter D. Howes

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4<i>H</i>-pyran-6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Journal of Medicinal Chemistry · 1998 · 339 citations · Full text

Greater Inhibitory Activity, New Series, Antiviral Drug +16

Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 2. Crystallographic and Molecular Modeling Study of Complexes of 4-Amino-4<i>H</i>-pyran-6-carboxamides and Sialidase from Influenza Virus Types A and B

Neil R. Taylor, Anne Cleasby, Onkar Singh et al. · Journal of Medicinal Chemistry · 1998 · 193 citations · Full text

Carboxamide Analogues, Protein Assembly, New Series +19

Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate

Martin J. Slater, Elizabeth M. Amphlett, David Andrews et al. · Journal of Medicinal Chemistry · 2007 · 90 citations

Hcv Replicon, Development Candidate, Molecular Biology +18

Total Synthesis of Cavicularin and Riccardin C: Addressing the Synthesis of an Arene That Adopts a Boat Configuration

Timothy Woodcock, Peter D. Howes · Angewandte Chemie International Edition · 2005 · 72 citations

Medicinal Chemistry, Natural Product Synthesis, Bioorganic Chemistry +11

Novel inhibitors of influenza sialidases related to GG167 structure-activity, crystallographic and Molecular dynamics studies with 4H-pyran-2-carboxylic acid 6-carboxamides

Paul W. Smith, Steven L. Sollis, Peter D. Howes et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 55 citations

Medicinal Chemistry, Biochemistry, Influenza Sialidases +10