Brian S. Safina

A Mild and Selective Method for the Hydrolysis of Esters with Trimethyltin Hydroxide

K. C. Nicolaou, Anthony A. Estrada, Mark Zak et al. · Angewandte Chemie International Edition · 2005 · 365 citations

Derivative (Chemistry), Trimethyltin Hydroxide, Engineering +11

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

Shivani Ahuja, Susmith Mukund, Lunbin Deng et al. · Science · 2015 · 322 citations · Full text

Voltage-gated Sodium, Molecular Biology, Molecular Pharmacology +18

Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity

Shelley E. Ackerman, Cecelia I. Pearson, Joshua D. Gregorio et al. · Nature Cancer · 2020 · 194 citations · Full text

Tumor Immunology, Cancer Immunosurveillance, Immunology +11

Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors

James F. Blake, Rui Xu, Josef R. Bencsik et al. · Journal of Medicinal Chemistry · 2012 · 184 citations · Full text

Human Tumors, Tumor Biology, Medicinal Chemistry +15

Total Synthesis of Thiostrepton. Retrosynthetic Analysis and Construction of Key Building Blocks

K. C. Nicolaou, Brian S. Safina, Mark Zak et al. · Journal of the American Chemical Society · 2005 · 130 citations