Josef R. Bencsik

Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors

James F. Blake, Rui Xu, Josef R. Bencsik et al. · Journal of Medicinal Chemistry · 2012 · 184 citations · Full text

Human Tumors, Tumor Biology, Medicinal Chemistry +15

Discovery and SAR of spirochromane Akt inhibitors

Nicholas C. Kallan, Keith L. Spencer, James F. Blake et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 42 citations · Full text

Medicinal Chemistry, Medicine, Mechanism Of Action +6

Diversification of the Three-Component Coupling of 2-Aminoheterocycles, Aldehydes, and Isonitriles: Efficient Parallel Synthesis of a Diverse and Druglike Library of Imidazo- and Tetrahydroimidazo[1,2-<i>a</i>] Heterocycles

Timothy Kercher, Chang Rao, Josef R. Bencsik et al. · Journal of Combinatorial Chemistry · 2007 · 40 citations

Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

Josef R. Bencsik, Dengming Xiao, James F. Blake et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 37 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +8

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators

Xiaohui Du, Ronald J. Hinklin, Yumei Xiong et al. · ACS Medicinal Chemistry Letters · 2014 · 15 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15