John A. Josey

Targeting renal cell carcinoma with a HIF-2 antagonist

Wenfang Chen, Haley Hill, Alana Christie et al. · Nature · 2016 · 697 citations · Full text

Urology, Genitourinary Cancer, Renal Cell Carcinoma +4

Antisense and Antigene Properties of Peptide Nucleic Acids

Jeffery C. Hanvey, Nancy J. Peffer, John Bisi et al. · Science · 1992 · 536 citations

Peptide Nucleic Acids, Nucleic Acid Chemistry, Protein Expression +14

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

Hyejin Cho, Xinlin Du, James P. Rizzi et al. · Nature · 2016 · 441 citations · Full text

Urology, Oncology, Hif-2α Antagonist +7

Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma

Kevin D. Courtney, Jeffrey R. Infante, Elaine T. Lam et al. · Journal of Clinical Oncology · 2017 · 369 citations · Full text

Peripheral Edema, Tumor Biology, Conclusion Pt2385 +12

A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma

Eli M. Wallace, James P. Rizzi, Guangzhou Han et al. · Cancer Research · 2016 · 310 citations