Shelley E. Ackerman

Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity

Shelley E. Ackerman, Cecelia I. Pearson, Joshua D. Gregorio et al. · Nature Cancer · 2020 · 203 citations · Full text

Medicine, Immunology, Oncology +16

<i>Streptococcus pneumoniae</i> secretes hydrogen peroxide leading to DNA damage and apoptosis in lung cells

Prashant Rai, Marcus C. Parrish, Ian J. Tay et al. · Proceedings of the National Academy of Sciences · 2015 · 141 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Targeted Drug Delivery with an Integrin-Binding Knottin–Fc–MMAF Conjugate Produced by Cell-Free Protein Synthesis

Nicolas Currier, Shelley E. Ackerman, James R. Kintzing et al. · Molecular Cancer Therapeutics · 2016 · 35 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Abstract OT-03-02: Phase 1/2 study of a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), BDC-1001, as a single agent and in combination with an immune checkpoint inhibitor in patients with advanced HER2-expressing solid tumors

Ecaterina Ileana Dumbrava, Manish Sharma, Richard D. Carvajal et al. · Cancer Research · 2021 · 17 citations

Medicine, Oncology, Pharmacology +17

Abstract 1559: TLR7/8 immune-stimulating antibody conjugates elicit robust myeloid activation leading to enhanced effector function and anti-tumor immunity in pre-clinical models

Shelley E. Ackerman, Joseph C. González, Josh Gregorio et al. · Cancer Research · 2019 · 11 citations

Medicine, Immunology, Oncology +17