Zhipei Wu

2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

S. KLUTCHKO, James M. Hamby, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 1998 · 130 citations · Full text

Cell Cycle and Biochemical Effects of PD 0183812

David W. Fry, David C. Bedford, Patricia H. Harvey et al. · Journal of Biological Chemistry · 2001 · 107 citations · Full text

Synthesis and Tyrosine Kinase Inhibitory Activity of a Series of 2-Amino-8<i>H</i>-pyrido[2,3-<i>d</i>]pyrimidines:  Identification of Potent, Selective Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors

Diane H. Boschelli, Zhipei Wu, S. KLUTCHKO et al. · Journal of Medicinal Chemistry · 1998 · 84 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Pharmacotherapy +17

Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain

Esteban Domı́nguez, Smriti Iyengar, Harlan E. Shannon et al. · Journal of Medicinal Chemistry · 2005 · 38 citations · Full text

Pain Therapy, Pain Medicine, Neuropathic Pain +19

Discovery of <i>N</i>-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3<i>R</i>)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model

Kevin R. Fales, F. George Njoroge, Harold B. Brooks et al. · Journal of Medicinal Chemistry · 2017 · 33 citations · Full text

Pharmacotherapy, Cancer Xenograft Model, Pharmaceutical Chemistry +18