Kevin R. Fales - Concepedia

Author

Kevin R. Fales

Eli Lilly (United States)ORCID

Also Known As

Fales, K.R., K. R. FALES, Kevin R. Fales

Publications

279

Citations

H-Index

Concepts

All Affiliations

Eli Lilly (United States)Eli Lilly (Spain)

About

Kevin R. Fales is an author at Eli Lilly (United States) specializing in medicine, pharmacology, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	206
2	Natural Sciences	2	2	27
3	Biochemistry	2	2	27
4	Biomolecular Engineering	1	1	58
5	Cell Biology	1	1	101

Kevin R. Fales

Publications

272

Citations

H-Index

Page 1

	Year	Citations
A Novel CDK9 Inhibitor Shows Potent Antitumor Efficacy in Preclinical Hematologic Tumor Models Tinggui Yin, Marı́a José Lallena, Emiko L. Kreklau, Molecular Cancer Therapeutics Tumor BiologyMedicineMalignant Blood DisorderImmunologyCell Death	2014	101
Asymmetric synthesis of cis-(−)-(2R4S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist Jerry W. Skiles, Peter P. Giannousis, Kevin R. Fales Bioorganic & Medicinal Chemistry Letters MedicineDrug DiscoveryAsymmetric SynthesisPharmacological AgentStereoselective Synthesis	1996	58
Discovery of <i>N</i>-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3<i>R</i>)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model Kevin R. Fales, F. George Njoroge, Harold B. Brooks, Journal of Medicinal Chemistry PharmacotherapyCancer Xenograft ModelPharmaceutical ChemistryTumor BiologyMolecular Pharmacology	2017	33
Synthesis of nine-membered carbocycles via sequential higher-order cycloaddition--pinacol rearrangement James H. Rigby, Kevin R. Fales Tetrahedron Letters Organic ChemistryPinacol RearrangementChemistryHeterocycle Chemistry	1998	22
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models Harold B. Brooks, Timothy I. Meier, Sandaruwan Geeganage, Scientific Reports	2018	20
Macrolactamization via Palladium .pi.-Allyl Alkylation. Preparation of CGS25155: A 10-Membered Lactam Neutral Endopeptidase 24.11 Inhibitor Erik P. Johnson, Guang‐Pei Chen, Kevin R. Fales, The Journal of Organic Chemistry Medicinal ChemistryPalladium .Pi.-allyl AlkylationBiochemistryMedicineNatural Sciences	1995	14
Enantioselective Synthesis of 3,3-Difluoropyrrolidin-4-ol, a Valuable Building Block in Medicinal Chemistry Chong Si, Kevin R. Fales, Alicia Torrado, The Journal of Organic Chemistry Asymmetric CatalysisMedicinal ChemistryBioorganic ChemistryBiochemistryNatural Sciences	2016	13
Higher-order cycloaddition reactions in synthesis. Asymmetric assembly of the C5C11 segment of the ansa bridge of streptovaricin D James H. Rigby, Kevin R. Fales Tetrahedron Letters	1998	11

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