Harold B. Brooks

X-ray Structure of Ornithine Decarboxylase from <i>Trypanosoma</i> <i>brucei</i>:  The Native Structure and the Structure in Complex with α-Difluoromethylornithine^,

Nick V. Grishin, Andrei L. Osterman, Harold B. Brooks et al. · Biochemistry · 1999 · 143 citations

X-ray Crystallography, Dependent Homodimeric Enzyme, Crystal Structure +21

Characterization of LY2228820 Dimesylate, a Potent and Selective Inhibitor of p38 MAPK with Antitumor Activity

Robert M. Campbell, Bryan D. Anderson, Nathan A. Brooks et al. · Molecular Cancer Therapeutics · 2013 · 115 citations

Drug Target, Antitumor Activity, P38 Mapk +20

Kinetic Characterization of Novel Pyrazole TGF-β Receptor I Kinase Inhibitors and Their Blockade of the Epithelial−Mesenchymal Transition

Sheng-Bin Peng, Lei Yan, Xiaoling Xia et al. · Biochemistry · 2005 · 99 citations

Synthesis, Structure−Activity Relationship, and Biological Studies of Indolocarbazoles as Potent Cyclin D1-CDK4 Inhibitors

Guoxin Zhu, Scott E. Conner, Xun Zhou et al. · Journal of Medicinal Chemistry · 2003 · 94 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Heterocyclic +14

Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases

Chafiq Hamdouchi, Boyu Zhong, J. S. MENDOZA et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 90 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +12