Jerry W. Skiles

A novel, dipyridodiazepinone inhibitor of HIV-1 reverse transcriptase acts through a nonsubstrate binding site

Joseph C. Wu, Thomas C. Warren, Julian Adams et al. · Biochemistry · 1991 · 181 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Spiro indolinone beta-lactams, inhibitors of poliovirus and rhinovlrus 3C-proteinases

Jerry W. Skiles, Daniel W. McNeil · Tetrahedron Letters · 1990 · 164 citations

Life Sciences, Medicinal Chemistry, Microbiology +12

Discovery of Potent, Selective, and Orally Active Carboxylic Acid Based Inhibitors of Matrix Metalloproteinase-13

Lauren G. Monovich, Rubén Tommasi, Roger A. Fujimoto et al. · Journal of Medicinal Chemistry · 2009 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Asymmetric synthesis of cis-(−)-(2R4S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist

Jerry W. Skiles, Peter P. Giannousis, Kevin R. Fales · Bioorganic & Medicinal Chemistry Letters · 1996 · 58 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Angiotensin-converting enzyme inhibitors: new orally active 1,4-thiazepine-2,5-diones, 1,4-thiazine-2,5-diones, and 1,4-benzothiazepine-2,5-diones possessing antihypertensive activity

Jerry W. Skiles, John T. Suh, Bruce Williams et al. · Journal of Medicinal Chemistry · 1986 · 53 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9