S. KLUTCHKO

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

William C. Patt, Harriet W. Hamilton, Michael D. Taylor et al. · Journal of Medicinal Chemistry · 1992 · 371 citations · Full text

Medicinal Chemistry, Hypertension, Renin Inhibitors +13

Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype

C. John Blankley, John C. Hodges, S. KLUTCHKO et al. · Journal of Medicinal Chemistry · 1991 · 161 citations · Full text

Pharmacotherapy, Ang Ii, Medicinal Chemistry +16

2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

S. KLUTCHKO, James M. Hamby, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 1998 · 130 citations · Full text

Anti-Angiogenic Activity of Selected Receptor Tyrosine Kinase Inhibitors, PD166285 and PD173074: Implications for Combination Treatment with Photodynamic Therapy

Charles J. Dimitroff, Wayne D. Klohs, Amarnath Sharma et al. · Investigational New Drugs · 1999 · 96 citations

Anti-angiogenic Activity, Angiogenesis, Photodynamic Therapy +11

In Vitro Pharmacological Characterization of PD 166285, a New Nanomolar Potent and Broadly Active Protein Tyrosine Kinase Inhibitor

Robert L. Panek, Gina H. Lu, S. KLUTCHKO et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 94 citations