Dagmar Aimová

Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice

Volker M. Arlt, Marie Stiborová, Colin J. Henderson et al. · Carcinogenesis · 2007 · 143 citations · Full text

Medicine, Pharmacokinetics, Toxicology +17

The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and Ellipticine<b><i>N</i></b>2-Oxide

Marie Stiborová, Jan Sejbal, Lucie Bořek-Dohalská et al. · Cancer Research · 2004 · 133 citations

Medicine, Biochemistry, Pharmacology +11

DNA adduct formation by the anticancer drug ellipticine in rats determined by ³²P postlabeling

Marie Stiborová, Andrea Breuer, Dagmar Aimová et al. · International Journal of Cancer · 2003 · 74 citations · Full text

Medicine, Biochemistry, Pharmacology +11

DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells

Jitka Poljaková, Eva Frei, Dagmar Aimová et al. · Cancer Letters · 2007 · 42 citations

Medicine, Oncology, Pharmacology +8

The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism

Dagmar Aimová, Lucie Svobodová, Věra Kotrbová et al. · Drug Metabolism and Disposition · 2007 · 39 citations

Medicine, Biochemistry, Pharmacology +17