Lucie Bořek-Dohalská

The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and Ellipticine<b><i>N</i></b>2-Oxide

Marie Stiborová, Jan Sejbal, Lucie Bořek-Dohalská et al. · Cancer Research · 2004 · 133 citations

Medicine, Biochemistry, Pharmacology +11

Ellipticine cytotoxicity to cancer cell lines - a comparative study

Marie Stiborová, Jitka Poljaková, Eva Martínková et al. · Interdisciplinary Toxicology · 2011 · 81 citations · Full text

Medicine, Oncology, Pharmacology +17

Rat Microsomes Activating the Anticancer Drug Ellipticine to Species Covalently Binding to Deoxyguanosine in DNA Are a Suitable Model Mimicking Ellipticine Bioactivation in Humans

Marie Stiborová, Martina Stiborová‐Rupertová, Lucie Bořek-Dohalská et al. · Chemical Research in Toxicology · 2002 · 69 citations

Medicine, Biochemistry, Pharmacology +15

α-Naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6

Lucie Bořek-Dohalská, Petr Hodek, Miroslav Šulc et al. · Chemico-Biological Interactions · 2001 · 39 citations

Medicine, Pharmacokinetics, Pharmacology +4

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen

Marie Stiborová, Lucie Bořek-Dohalská, Petr Hodek et al. · Archives of Biochemistry and Biophysics · 2002 · 38 citations

Medicine, Oncology, Pharmacology +12