Věra Kotrbová - Concepedia

Author

Věra Kotrbová

Charles University

Also Known As

Vera Kotrbova, Věra Kotrbová

Publications

255

Citations

H-Index

Concepts

All Affiliations

Charles University German Cancer Research Center Heidelberg University Institute of Cancer Research

About

Věra Kotrbová is an author at Charles University specializing in medicine, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	163
2	Biochemistry	4	4	163
3	Metabolism	2	2	97
4	Engineering	1	1	17
5	Microbiology	1	1	17

Věra Kotrbová

Publications

240

Citations

H-Index

Page 1

	Year	Citations
Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model Kateřina Levová, Michaela Moserová, Věra Kotrbová, Toxicological Sciences Aristolochic AcidLipid PeroxidationAai DemethylationCarcinogenic Aristolochic AcidRedox Biology	2011	54
Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy Věra Kotrbová, Barbora Mrázová, Michaela Moserová, Biochemical Pharmacology Pharmacological EfficacyBiochemistryMedicineLipid PeroxidationMechanism Of Action	2011	49
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse Marie Stiborová, Volker M. Arlt, Colin J. Henderson, Toxicology and Applied Pharmacology OxysterolHepatic NadphBiochemistryMedicineLiver Physiology	2007	43
The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Drug Metabolism and Disposition	2007	39
Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method Michaela Moserová, Věra Kotrbová, Dagmar Aimová, Interdisciplinary Toxicology	2009	28
Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli Věra Kotrbová, Dagmar Aimová, Marek Ingr, Protein Expression and Purification BiosynthesisEngineeringBiochemistryEnzyme CatalysisBiocatalysis	2009	17
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2 Dagmar Aimová, Jitka Poljaková, Věra Kotrbová, Interdisciplinary Toxicology	2008	10

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