Věra Kotrbová

Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model

Kateřina Levová, Michaela Moserová, Věra Kotrbová et al. · Toxicological Sciences · 2011 · 54 citations · Full text

Aristolochic Acid, Lipid Peroxidation, Aai Demethylation +16

Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy

Věra Kotrbová, Barbora Mrázová, Michaela Moserová et al. · Biochemical Pharmacology · 2011 · 49 citations · Full text

Pharmacological Efficacy, Biochemistry, Medicine +9

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

Marie Stiborová, Volker M. Arlt, Colin J. Henderson et al. · Toxicology and Applied Pharmacology · 2007 · 43 citations

Oxysterol, Hepatic Nadph, Biochemistry +10

The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism

Dagmar Aimová, Lucie Svobodová, Věra Kotrbová et al. · Drug Metabolism and Disposition · 2007 · 39 citations

Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

Michaela Moserová, Věra Kotrbová, Dagmar Aimová et al. · Interdisciplinary Toxicology · 2009 · 28 citations · Full text