Michaela Moserová

The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[<i>a</i>]pyrene in human livers

Miroslav Šulc, Radek Indra, Michaela Moserová et al. · Environmental and Molecular Mutagenesis · 2016 · 82 citations · Full text

Medicine, Pharmacology, Toxicology +17

Role of Cytochromes P450 1A1/2 in Detoxication and Activation of Carcinogenic Aristolochic Acid I: Studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) Mouse Model

Kateřina Levová, Michaela Moserová, Věra Kotrbová et al. · Toxicological Sciences · 2011 · 54 citations · Full text

Pharmacy, Biochemistry, Toxicology +15

Cytochrome b5 shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy

Věra Kotrbová, Barbora Mrázová, Michaela Moserová et al. · Biochemical Pharmacology · 2011 · 49 citations

Medicine, Biochemistry, Pharmacology +17

Cytochrome b and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

Marie Stiborová, Michaela Moserová, Věra Černá et al. · Toxicology · 2014 · 44 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/–) and Trp53(−/−) mice

Annette M. Krais, Ewoud N. Speksnijder, Joost P.M. Melis et al. · Archives of Toxicology · 2015 · 44 citations · Full text

Medicine, Molecular Biology, Toxicology +17