Concepedia

The Anticancer Drug Ellipticine Is a Potent Inducer of Rat Cytochromes P450 1A1 and 1A2, Thereby Modulating Its Own Metabolism

Dagmar Aimová, Lucie Svobodová, Věra Kotrbová, Barbora Mrázová, Petr Hodek, Radka Václavíková, Eva Frei, Marie Stiborová

Drug Metabolism and Disposition · 2007 · 39 citations · 34 references

DOI

Concepts

References

34

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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Investigation of the bicinchoninic acid protein assay: Identification of the groups responsible for color formation

Karen J. Wiechelman, Robert D. Braun, J. D. Fitzpatrick · Analytical Biochemistry · 1988 · 756 citations

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Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Marie Stiborová, Václav Martínek, Helena Rýdlová et al. · PubMed · 2002 · 274 citations

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Constitutive Activation of the Aromatic Hydrocarbon Receptor

Ching‐yi Chang, Alvaro Puga · Molecular and Cellular Biology · 1998 · 244 citations · Full text

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The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts☆

Marie Stiborová, Christian A. Bieler, Eva Frei · Biochemical Pharmacology · 2001 · 148 citations

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