Václav Martínek

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Marie Stiborová, Václav Martínek, Helena Rýdlová et al. · PubMed · 2002 · 274 citations

Medicine, Pharmacology, Toxicology +16

Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols

Volker M. Arlt, Marie Stiborová, Colin J. Henderson et al. · Cancer Research · 2005 · 122 citations

Pharmacy, Biochemistry, Toxicology +15

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers

Marie Stiborová, Václav Martínek, Helena Rýdlová et al. · Cancer Letters · 2004 · 102 citations

Medicine, Biochemistry, Pharmacology +16

Modifying the β,γ Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase β

Christopher A. Sucato, Thomas G. Upton, B. A. Kashemirov et al. · Biochemistry · 2006 · 97 citations

Life Sciences, Biochemistry, Molecular Biology +16

Decomposition of the Solvation Free Energies of Deoxyribonucleoside Triphosphates Using the Free Energy Perturbation Method

Urban Bren, Václav Martínek, Jan Florián · The Journal of Physical Chemistry B · 2006 · 76 citations

Natural Sciences, Biochemistry, Chemistry +17