Colin J. Henderson

The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.

Michael McMahon, Ken Itoh, Masayuki Yamamoto et al. · PubMed · 2001 · 656 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo

Valerie Stock, Linda Böhmert, Elisa Lisicki et al. · Archives of Toxicology · 2019 · 593 citations · Full text

Natural Sciences, Pharmacokinetics, Toxicology +11

Feedback control of AHR signalling regulates intestinal immunity

Chris Schiering, Emma Wincent, Amina Metidji et al. · Nature · 2017 · 542 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

Simon A. Chanas, Qingwu Jiang, Michael McMahon et al. · Biochemical Journal · 2002 · 448 citations · Full text

Pharmacy, Genetics, Toxicology +17

Increased skin tumorigenesis in mice lacking pi class glutathione <i>S</i> -transferases

Colin J. Henderson, Austin Smith, Jan Ure et al. · Proceedings of the National Academy of Sciences · 1998 · 375 citations · Full text

Medicine, Cancer Biology, Oncology +17