Takuo Kosaka

Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin

Yasuaki Itoh, Masashi Yanagisawa, Shoichi Ohkubo et al. · FEBS Letters · 1988 · 401 citations · Full text

Life Sciences, Physiology, Developmental Physiology +10

Synthesis of the vasoconstrictor peptide endothelin in kidney cells

Takuo Kosaka, Nobuhiro Suzuki, Hirokazu Matsumoto et al. · FEBS Letters · 1989 · 99 citations · Full text

Life Sciences, Cell Biology, Physiology +8

Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism

Charles E. Grimshaw, Andy Jennings, Ruhi Kamran et al. · PLoS ONE · 2016 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta

Haruo Onda, Shoichi Ohkubo, Kazuhiro Ogi et al. · FEBS Letters · 1990 · 58 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Discovery of a 3-Pyridylacetic Acid Derivative (TAK-100) as a Potent, Selective and Orally Active Dipeptidyl Peptidase IV (DPP-4) Inhibitor

Yasufumi Miyamoto, Yoshihiro Banno, Tatsuhiko Fujimoto et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17