Abdellah Tahri

TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates

Sandra De Meyer, Hilde Azijn, Dominique Surleraux et al. · Antimicrobial Agents and Chemotherapy · 2005 · 357 citations

Life Sciences, Infectious Diseases, Molecular Biology +17

Discovery and Selection of TMC114, a Next Generation HIV-1 Protease Inhibitor

Dominique Surleraux, Abdellah Tahri, Wim G. Verschueren et al. · Journal of Medicinal Chemistry · 2004 · 256 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Structure–activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350

Pierre Raboisson, Herman de Kock, Åsa Rosenquist et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis of α-carbolines and β-carbolinones via intramolecular Diels-Alder reactions of 2(1H)-pyrazinones

Abdellah Tahri, Kris J. Buysens, Erik V. Van der Eycken et al. · Tetrahedron · 1998 · 64 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase

Koen Vandyck, Maxwell D. Cummings, Origène Nyanguile et al. · Journal of Medicinal Chemistry · 2009 · 60 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16