Origène Nyanguile - Concepedia

Author

Origène Nyanguile

Also Known As

Nyanguile, Origène, O Nyanguile, O. Nyanguile, Origene Nyanguile, Origène Nyanguile, Origène F. Nyanguile, Origène Nyanguile

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Janssen (Belgium)HES-SO Valais-Wallis Harvard University École Polytechnique Fédérale de Lausanne Research Institute for Genetic and Human Therapy

About

Origène Nyanguile is an author at Janssen (Belgium) specializing in medicine, molecular biology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	275
2	Natural Sciences	5	5	189
3	Biomolecular Engineering	3	3	119
4	Biochemistry	2	2	84
5	Engineering	1	1	38

Origène Nyanguile

Publications

Citations

H-Index

Page 1

	Year	Citations
Induced α Helix in the VP16 Activation Domain upon Binding to a Human TAF Motonari Uesugi, Origène Nyanguile, Hua Lu, Science	1997	289
Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents Ilia Fishbein, Ivan S. Alferiev, Origène Nyanguile, Proceedings of the National Academy of Sciences	2005	95
Binding-Site Identification and Genotypic Profiling of Hepatitis C Virus Polymerase Inhibitors Frederik Pauwels, Wendy Mostmans, Ludo Quirynen, Journal of Virology	2007	67
Structure-Based Design of a Benzodiazepine Scaffold Yields a Potent Allosteric Inhibitor of Hepatitis C NS5B RNA Polymerase Koen Vandyck, Maxwell D. Cummings, Origène Nyanguile, Journal of Medicinal Chemistry	2009	60
A nonnatural transcriptional coactivator Origène Nyanguile, Motonari Uesugi, David Austin, Proceedings of the National Academy of Sciences	1997	60
A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading Vanessa Gaillard, Marie Galloux, Dominique Garcin, Antimicrobial Agents and Chemotherapy Protease InhibitorsViral ReplicationSynthetic VirologyRespiratory DiseasesProtein Folding	2017	51
Antiviral Suppression vs Restoration of RIG-I Signaling by Hepatitis C Protease and Polymerase Inhibitors Yuqiong Liang, Hisashi Ishida, Oliver Lenz, Gastroenterology Hepatitis C ProteaseViral HepatitisMedicineImmunologyAntiviral Drug Development	2008	47
1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, Antimicrobial Agents and Chemotherapy Molecular BiologyPharmacotherapyAntiviral DrugChemical BiologyAntiviral Drug Development	2008	45
TMC647055, a Potent Nonnucleoside Hepatitis C Virus NS5B Polymerase Inhibitor with Cross-Genotypic Coverage Benoit Devogelaere, Jan Martin Berke, Leen Vijgen, Antimicrobial Agents and Chemotherapy Vitro Inhibitory ActivityHepatologyCross-genotypic CoverageViral HepatitisMedicine	2012	43
Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055 Sandrine Vendeville, Tse‐I Lin, Lili Hu, Bioorganic & Medicinal Chemistry Letters Hcv Ns5b PolymeraseBiochemistryNatural SciencesAntiviral Drug DevelopmentMolecular Biology	2012	39

Page 1