Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus

Jan Martin Berke, Pascale Dehertogh, Karen Vergauwen, +4

Antimicrobial Agents and Chemotherapy

Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379

Jan Martin Berke, Pascale Dehertogh, Karen Vergauwen, +4

Antimicrobial Agents and Chemotherapy

Binding-Site Identification and Genotypic Profiling of Hepatitis C Virus Polymerase Inhibitors

Frederik Pauwels, Wendy Mostmans, Ludo Quirynen, +8

Journal of Virology

Minor Variant Detection in Amplicons using 454 Massive Parallel Pyrosequencing: Experiences and Considerations for Successful Applications

Ina Vandenbroucke, Herwig Van Marck, Peter Verhasselt, +7

BioTechniques

1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside Inhibitors

Origène Nyanguile, Frederik Pauwels, Walter Van den Broeck, +12

Antimicrobial Agents and Chemotherapy

Molecular BiologyPharmacotherapyAntiviral DrugChemical BiologyAntiviral Drug Development +15

Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus

David C. McGowan, Florence Herschke, Frederik Pauwels, +18

Journal of Medicinal Chemistry

Internal Screening EffortViral HepatitisMedicineImmunologyDual Agonists +13

1a/1b Subtype Profiling of Nonnucleoside Polymerase Inhibitors of Hepatitis C Virus

Origène Nyanguile, Benoit Devogelaere, Leen Vijgen, +19

Journal of Virology

EngineeringHepatitis C VirusMolecular BiologyPathologyPalm-1 Binding Site +17

HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays

Ina Vandenbroucke, Herwig Van Marck, Wendy Mostmans, +13

AIDS Research and Therapy

HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro

Valentina Svicher, E Balestra, Valeria Cento, +15

Antiviral Research

Phenotypic CharacteristicsHuman RetrovirusHiv-1 Dual/mixed TropicPathogenesisImmunology +7

2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus

Werner Embrechts, Florence Herschke, Frederik Pauwels, +19

Journal of Medicinal Chemistry

ImmunologyAmino AlcoholDual Toll-like ReceptorPharmacotherapyAntiviral Drug +16