Koen Vandyck

Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: Results from two randomized, double-blind, placebo-controlled studies with single oral doses

Gary Herman, C. Melinda Stevens, Koen Vandyck et al. · Clinical Pharmacology & Therapeutics · 2005 · 514 citations

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor <i>In Vitro</i> and Confer Resistance To Nirmatrelvir

Dirk Jochmans, Kim Donckers, Antitsa Stoycheva et al. · mBio · 2023 · 163 citations · Full text

Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus

Jan Martin Berke, Pascale Dehertogh, Karen Vergauwen et al. · Antimicrobial Agents and Chemotherapy · 2017 · 149 citations · Full text

Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

Thomas Lahlali, Jan Martin Berke, Karen Vergauwen et al. · Antimicrobial Agents and Chemotherapy · 2018 · 96 citations · Full text

Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379

Jan Martin Berke, Pascale Dehertogh, Karen Vergauwen et al. · Antimicrobial Agents and Chemotherapy · 2020 · 70 citations · Full text