Kirsten Bell

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

Michael Hedvat, Dennis Huszar, Andreas Herrmann et al. · Cancer Cell · 2009 · 529 citations · Full text

Medicine, Oncology, Pharmacology +9

Discovery of 5-Chloro-<i>N</i>²-[(1<i>S</i>)-1-(5-fluoropyrimidin-2-yl)ethyl]-<i>N</i>⁴-(5-methyl-1<i>H</i>-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway

Stephanos Ioannidis, Michelle L. Lamb, Tao Wang et al. · Journal of Medicinal Chemistry · 2010 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Absence of Mitochondrial Superoxide Dismutase Results in a Murine Hemolytic Anemia Responsive to Therapy with a Catalytic Antioxidant

Jeff S. Friedman, Vivienne I. Rebel, Ryan Derby et al. · The Journal of Experimental Medicine · 2001 · 78 citations · Full text

Life Sciences, Cell Biology, Hematology +16

Discovery of (2<i>R</i>)-<i>N</i>-[3-[2-[(3-Methoxy-1-methyl-pyrazol-4-yl)amino]pyrimidin-4-yl]-1<i>H</i>-indol-7-yl]-2-(4-methylpiperazin-1-yl)propenamide (AZD4205) as a Potent and Selective Janus Kinase 1 Inhibitor

Qibin Su, Erica Banks, Geraldine Bebernitz et al. · Journal of Medicinal Chemistry · 2020 · 60 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +15

Discovery of 1-Methyl-1<i>H</i>-imidazole Derivatives as Potent Jak2 Inhibitors

Qibin Su, Stephanos Ioannidis, Claudio Chuaqui et al. · Journal of Medicinal Chemistry · 2013 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13