Claudio Chuaqui

Structural Interaction Fingerprint (SIFt):  A Novel Method for Analyzing Three-Dimensional Protein−Ligand Binding Interactions

Zhan Deng, Claudio Chuaqui, Juswinder Singh · Journal of Medicinal Chemistry · 2003 · 562 citations

Structural Interaction Fingerprint, Structural Bioinformatics, Molecular Biology +19

Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)

Richard A. Ward, Mark J. Anderton, Susan Ashton et al. · Journal of Medicinal Chemistry · 2013 · 257 citations · Full text

Covalent Inhibitors, Drug Target, Thiol Reactivity +19

Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain

Gizem Akçay, Matthew A. Belmonte, Brian Aquila et al. · Nature Chemical Biology · 2016 · 191 citations · Full text

Protein Chemistry, Medicinal Chemistry, Biochemistry +8

Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)

Juswinder Singh, Claudio Chuaqui, P. Ann Boriack‐Sjodin et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 166 citations · Full text

Virtual Screening, Tgfβ Receptor Kinase, Engineering +8

Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1

Jiaquan Wu, Keith Mikule, Wenxian Wang et al. · ACS Chemical Biology · 2013 · 120 citations

Molecular Biology, Small Molecule Inhibitor, Cytoskeleton +21