Jiaquan Wu

Structural Basis of Substrate Methylation and Inhibition of SMYD2

Andrew D. Ferguson, Nicholas Larsen, Tina Howard et al. · Structure · 2011 · 193 citations · Full text

Biochemistry, Natural Sciences, Epigenetic Change +7

Mechanism and <i>In Vitro</i> Pharmacology of TAK1 Inhibition by (5<i>Z</i>)-7-Oxozeaenol

Jiaquan Wu, Francoise Powell, Nicholas Larsen et al. · ACS Chemical Biology · 2012 · 142 citations

Cancer Biology, Tumor Biology, Molecular Pharmacology +20

Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1

Jiaquan Wu, Keith Mikule, Wenxian Wang et al. · ACS Chemical Biology · 2013 · 120 citations

Molecular Biology, Small Molecule Inhibitor, Cytoskeleton +21

Effects of the JAK2 Inhibitor, AZ960, on Pim/BAD/BCL-xL Survival Signaling in the Human JAK2 V617F Cell Line SET-2

Joseph M. Gozgit, Geraldine Bebernitz, Pankaj Patil et al. · Journal of Biological Chemistry · 2008 · 101 citations · Full text

Polyketide Double Bond Biosynthesis. Mechanistic Analysis of the Dehydratase-Containing Module 2 of the Picromycin/Methymycin Polyketide Synthase

Jiaquan Wu, Toby J. Zaleski, Chiara R. Valenzano et al. · Journal of the American Chemical Society · 2005 · 81 citations · Full text

Dehydratase-containing Module 2, Picromycin/methymycin Synthase, Engineering +18