Chiara R. Valenzano

Polyketide Double Bond Biosynthesis. Mechanistic Analysis of the Dehydratase-Containing Module 2 of the Picromycin/Methymycin Polyketide Synthase

Jiaquan Wu, Toby J. Zaleski, Chiara R. Valenzano et al. · Journal of the American Chemical Society · 2005 · 81 citations · Full text

Dehydratase-containing Module 2, Picromycin/methymycin Synthase, Engineering +18

The Biochemical Basis for Stereochemical Control in Polyketide Biosynthesis

Chiara R. Valenzano, Rachel J. Lawson, Alice Y. Chen et al. · Journal of the American Chemical Society · 2009 · 76 citations · Full text

Synthetic Macromolecule, Biosynthesis, Engineering +15

Stereospecificity of the Dehydratase Domain of the Erythromycin Polyketide Synthase

Chiara R. Valenzano, Young-Ok You, Ashish Garg et al. · Journal of the American Chemical Society · 2010 · 75 citations

Dehydration Product, Biosynthesis, Biochemistry +11

Identification of NanE as the Thioesterase for Polyether Chain Release in Nanchangmycin Biosynthesis

Tiangang Liu, Delin You, Chiara R. Valenzano et al. · Chemistry & Biology · 2006 · 63 citations

Biosynthesis, Engineering, Biochemistry +9

A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death

Duncan E. Scott, Nicola J. Francis-Newton, M. Marsh et al. · Cell chemical biology · 2021 · 51 citations · Full text