Keith Mikule

Suppression of cancer relapse and metastasis by inhibiting cancer stemness

Youzhi Li, Harry A. Rogoff, Sarah Keates et al. · Proceedings of the National Academy of Sciences · 2015 · 451 citations · Full text

Cancer Relapse, Cancer Biology, Tumor Biology +16

Loss of centrosome integrity induces p38—p53—p21-dependent G1—S arrest

Keith Mikule, Bénédicte Delaval, Philipp Kaldis et al. · Nature Cell Biology · 2006 · 310 citations

Cell Regulation, Cell Division, Medicine +5

Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models

Zebin Wang, Kaiming Sun, Yonghong Xiao et al. · Scientific Reports · 2019 · 254 citations · Full text

A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models

Kaiming Sun, Keith Mikule, Zebin Wang et al. · Oncotarget · 2018 · 177 citations · Full text

Synthetic Lethality of PARP Inhibitors in Combination with MYC Blockade Is Independent of BRCA Status in Triple-Negative Breast Cancer

Jason P.W. Carey, Cansu Karakaş, Tuyen Bui et al. · Cancer Research · 2017 · 140 citations · Full text

Breast Oncology, Synthetic Lethality, Cancer Biology +19