A.J. Jennings

A Novel, Potent, and Selective 5-HT₇Antagonist:  (<i>R</i>)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)

Peter J. Lovell, Steven M. Bromidge, Steven Dabbs et al. · Journal of Medicinal Chemistry · 2000 · 248 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

(<i>R</i>)-3,<i>N</i>-Dimethyl-<i>N</i>-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide:  The First Selective 5-HT₇Receptor Antagonist

Ian T. Forbes, Steven Dabbs, D. Malcolm Duckworth et al. · Journal of Medicinal Chemistry · 1998 · 102 citations · Full text

Drug Target, Altmetric Attention Score, Pharmacotherapy +16

The Selective 5-HT_1BReceptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-<i>f</i>]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo

Laramie M. Gaster, Frank E. Blaney, Susannah Davies et al. · Journal of Medicinal Chemistry · 1998 · 81 citations · Full text

Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

Steven M. Bromidge, Stephen E. Clarke, Tracey Gager et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 56 citations · Full text

Selective 5-Ht6 Antagonists, Medicinal Chemistry, Derivative (Chemistry) +10

(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide

Laramie M. Gaster, A.J. Jennings, Graham F. Joiner et al. · Journal of Medicinal Chemistry · 1993 · 39 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +15