Characterization of SB‐269970‐A, a selective 5‐HT₇ receptor antagonist

Jim J. Hagan, Gary Price, Nigel Deeks, +10

British Journal of Pharmacology

A Novel, Potent, and Selective 5-HT₇Antagonist:  (<i>R</i>)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)

Peter J. Lovell, Steven M. Bromidge, Steven Dabbs, +11

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceTranslational PharmacologyBiochemistry +12

The identification of potent and selective imidazole-based inhibitors of B-Raf kinase

Andrew K. Takle, Murray J. B. Brown, Susannah Davies, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryB-raf KinaseNatural Sciences +9

(<i>R</i>)-3,<i>N</i>-Dimethyl-<i>N</i>-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide:  The First Selective 5-HT₇Receptor Antagonist

Ian T. Forbes, Steven Dabbs, D. Malcolm Duckworth, +10

Journal of Medicinal Chemistry

Drug TargetAltmetric Attention ScorePharmacotherapyChemical BiologyPharmaceutical Chemistry +14

Synthesis of Ellipticine:  A Radical Cascade Protocol to Aryl- and Heteroaryl-Annulated[<i>b</i>]carbazoles

Jan Pedersen, W. Russell Bowman, M.R.J. Elsegood, +2

The Journal of Organic Chemistry

Medicinal ChemistryDiversity Oriented SynthesisEngineeringHeterocyclicRadical Cascade Protocol +12

[³H]‐SB‐269970 – A selective antagonist radioligand for 5‐HT₇ receptors

David R. Thomas, Peter J. Atkinson, Michael Ho, +6

British Journal of Pharmacology

The Synthesis of Azadirachtin: A Potent Insect Antifeedant

Steven V. Ley, Antonio Abad‐Somovilla, James C. Anderson, +43

Chemistry - A European Journal

Combinatorial ChemistryFirst SynthesisHeterocyclicAntiparasitic AgentConvergent Approach +10

Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

Steven M. Bromidge, Stephen E. Clarke, Tracey Gager, +12

Bioorganic & Medicinal Chemistry Letters

Selective 5-Ht6 AntagonistsMedicinal ChemistryDerivative (Chemistry)MedicineDrug Discovery +8

New quinoline NK3 receptor antagonists with CNS activity

Paul W. Smith, Paul Wyman, Peter J. Lovell, +15

Bioorganic & Medicinal Chemistry Letters

Functional SelectivityMedicineImmunologyReceptor (Biochemistry)Neuropeptide Receptor +4

A Stille cyclisation approach to (−)-periplanone-B: studies in alkene-selective ring-closing metathesis and an improved chromium(II)-mediated synthesis of (E )-alkenylstannanes from aldehydes

David M. Hodgson, Anne M. Foley, Lee T. Boulton, +2

Journal of the Chemical Society Perkin Transactions 1

Cross-coupling ReactionDerivativesHeterocyclicAlkene-selective Ring-closing MetathesisDienone 7 +9