D. Malcolm Duckworth

A Novel, Potent, and Selective 5-HT₇Antagonist:  (<i>R</i>)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)

Peter J. Lovell, Steven M. Bromidge, Steven Dabbs et al. · Journal of Medicinal Chemistry · 2000 · 249 citations · Full text

Medicine, Chemistry, Pharmacology +5

(<i>R</i>)-3,<i>N</i>-Dimethyl-<i>N</i>-[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide:  The First Selective 5-HT₇Receptor Antagonist

Ian T. Forbes, Steven Dabbs, D. Malcolm Duckworth et al. · Journal of Medicinal Chemistry · 1998 · 102 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

The Selective 5-HT_1BReceptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-<i>f</i>]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo

Laramie M. Gaster, Frank E. Blaney, Susannah Davies et al. · Journal of Medicinal Chemistry · 1998 · 81 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Biarylcarbamoylindolines Are Novel and Selective 5-HT_2C Receptor Inverse Agonists:  Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a Potential Antidepressant/Anxiolytic Agent

Steven M. Bromidge, Steven Dabbs, David T. Davies et al. · Journal of Medicinal Chemistry · 2000 · 79 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Novel and Selective 5-HT_2C/2B Receptor Antagonists as Potential Anxiolytic Agents:  Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling of Substituted 1-(3-Pyridylcarbamoyl)indolines

Steven M. Bromidge, Steven Dabbs, David T. Davies et al. · Journal of Medicinal Chemistry · 1998 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17