Susannah Davies

The identification of potent and selective imidazole-based inhibitors of B-Raf kinase

Andrew K. Takle, Murray J. B. Brown, Susannah Davies et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 189 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +11

The Selective 5-HT_1BReceptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-<i>f</i>]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo

Laramie M. Gaster, Frank E. Blaney, Susannah Davies et al. · Journal of Medicinal Chemistry · 1998 · 81 citations · Full text

Biarylcarbamoylindolines Are Novel and Selective 5-HT_2C Receptor Inverse Agonists:  Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a Potential Antidepressant/Anxiolytic Agent

Steven M. Bromidge, Steven Dabbs, David T. Davies et al. · Journal of Medicinal Chemistry · 2000 · 79 citations · Full text

Potential Antidepressant/anxiolytic Agent, Psychotropic Medication, Inverse Agonists +18

(1H-Imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: A novel class of potent MSK-1-inhibitors

Mark J. Bamford, Michael J. Alberti, Nicholas Bailey et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 43 citations · Full text

-1,2,5-Oxadiazol-3-ylamine Derivatives, Medicinal Chemistry, Medicine +6

The identification of potent, selective and CNS penetrant furan-based inhibitors of B-Raf kinase

Andrew K. Takle, Mark J. Bamford, Susannah Davies et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 25 citations · Full text

Drug Target, Biochemistry, B-raf Kinase +9