M. Catherine Johnson

Structure-based design of novel human Pin1 inhibitors (I)

Chuangxing Guo, Xinjun Hou, Liming Dong et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Molecular Docking, Drug Target, Medicine +4

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Michael St. Andre, M. Catherine Johnson, Prashant Bansal et al. · Skeletal Muscle · 2017 · 98 citations · Full text

Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90

Ariamala Gopalsamy, Mengxiao Shi, Jennifer M. Golas et al. · Journal of Medicinal Chemistry · 2008 · 94 citations · Full text

Atp Binding Pocket, Drug Target, Protein Assembly +17

Structure-based design of novel human Pin1 inhibitors (II)

Liming Dong, Joseph Marakovits, Xinjun Hou et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 86 citations

Molecular Docking, Drug Target, Medicine +4

Discovery of Pyrroloaminopyrazoles as Novel PAK Inhibitors

Chuangxing Guo, Indrawan McAlpine, Junhu Zhang et al. · Journal of Medicinal Chemistry · 2012 · 59 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +15