Michael St. Andre

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

Michael St. Andre, M. Catherine Johnson, Prashant Bansal et al. · Skeletal Muscle · 2017 · 98 citations · Full text

Distinct protein degradation profiles are induced by different disuse models of skeletal muscle atrophy

Peter Bialek, Carl Morris, Jascha Parkington et al. · Physiological Genomics · 2011 · 58 citations

Muscle Function, Pathology, Skeletal Muscle Atrophy +16

Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody

James R. Apgar, Michelle Mader, Rita Agostinelli et al. · mAbs · 2016 · 49 citations · Full text

Immunocytochemical Technique, Immunology, Traditional Cdr-grafting +20

Treatment with rhBMP12 or rhBMP13 increase the rate and the quality of rat Achilles tendon repair

Scott A. Jelinsky, Li Li, Debra Ellis et al. · Journal of Orthopaedic Research® · 2011 · 38 citations · Full text

Engineering, Bone Repair, Orthopaedic Surgery +21

1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)indoline-4-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators

Eugene L. Piatnitski Chekler, Rayomond J. Unwalla, Taukeer A. Khan et al. · Journal of Medicinal Chemistry · 2014 · 18 citations · Full text

Androgen Receptor, Indoline-4-carbonitrile Derivatives, Pharmacotherapy +18