Eugene L. Piatnitski Chekler

Target validation using chemical probes

Mark E. Bunnage, Eugene L. Piatnitski Chekler, Lyn H. Jones · Nature Chemical Biology · 2013 · 431 citations · Full text

Method Validation, Engineering, Sample Preparation +9

Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects

Christina Schindler, Hannah M. Baumann, Andreas Blum et al. · Journal of Chemical Information and Modeling · 2020 · 292 citations

Transcriptional Profiling of a Selective CREB Binding Protein Bromodomain Inhibitor Highlights Therapeutic Opportunities

Eugene L. Piatnitski Chekler, Jessica Pellegrino, Thomas A. Lanz et al. · Chemistry & Biology · 2015 · 60 citations · Full text

Transcriptional Regulation, Transcriptional Profiling, Signaling Pathway +10

Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects

Christina Schindler, H Baumann, Andreas Blum et al. · 2020 · 51 citations · Full text

Drug Target, Engineering, Hit Identification +14

Kiloscale Buchwald–Hartwig Amination: Optimized Coupling of Base-Sensitive 6-Bromoisoquinoline-1-carbonitrile with (<i>S</i>)-3-Amino-2-methylpropan-1-ol

Jeffrey B. Sperry, Kristin E. Price Wiglesworth, Ian D. Edmonds et al. · Organic Process Research & Development · 2014 · 45 citations

Combinatorial Chemistry, Bioorganic Chemistry, Engineering +17