Mengxiao Shi

Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases

Jingsong Cao, Yingjiang Zhou, Haibing Peng et al. · Journal of Biological Chemistry · 2011 · 149 citations · Full text

Small Molecule Inhibitors, Metabolic Diseases, Metabolic Remodeling +18

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

Peter V.N. Bodine, Barbara Stauffer, Helga Ponce‐de‐Leon et al. · Bone · 2009 · 124 citations

Sclerostin, Signal Transduction, Bone Morphogenic Protein +12

Discovery of Benzisoxazoles as Potent Inhibitors of Chaperone Heat Shock Protein 90

Ariamala Gopalsamy, Mengxiao Shi, Jennifer M. Golas et al. · Journal of Medicinal Chemistry · 2008 · 94 citations · Full text

Atp Binding Pocket, Drug Target, Protein Assembly +17

Identification of pyrimidine derivatives as hSMG-1 inhibitors

Ariamala Gopalsamy, Eric M. Bennett, Mengxiao Shi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 93 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +6

Discovery of Dibenzo[<i>c</i>,<i>f</i>][2,7]naphthyridines as Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 Inhibitors

Ariamala Gopalsamy, Mengxiao Shi, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 2007 · 55 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +15