A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Saswata Talukdar, Yingjiang Zhou, Dongmei Li, +15

Cell Metabolism

ObesityMetabolic SyndromeLong-acting Fgf21 MoleculeGrowth HormoneMetabolic Disorder +10

FGF21 Regulates Sweet and Alcohol Preference

Saswata Talukdar, Bryn M. Owen, Parkyong Song, +13

Cell Metabolism

Metabolic SyndromeGeneticsAlcohol AbuseFgf21 Regulates SweetAlcohol Dependence

Regulation of glucose homeostasis through a XBP-1–FoxO1 interaction

Yingjiang Zhou, Justin Lee, Candace M. Reno, +8

Nature Medicine

Signal TransductionHomeostatic MechanismGlucose HomeostasisMetabolic RegulationCellular Biochemistry +4

The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation

Sang Won Park, Yingjiang Zhou, Justin Lee, +5

Nature Medicine

Transcriptional RegulationProtein FunctionSignal TransductionSignaling PathwayMolecular Regulation +10

Sarco(endo)plasmic reticulum Ca ²⁺ -ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity

Sang Won Park, Yingjiang Zhou, Jaemin Lee, +2

Proceedings of the National Academy of Sciences

Glucose HomeostasisEr StressMetabolic RemodelingEndoplasmic Reticulum StressSerca2b Protein +21

p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis

Jaemin Lee, Cheng Sun, Yingjiang Zhou, +6

Nature Medicine

Molecular PhysiologySignal TransductionBiochemistrySignaling PathwayNatural Sciences +8

Neuronal SH2B1 is essential for controlling energy and glucose homeostasis

Decheng Ren, Yingjiang Zhou, David L. Morris, +3

Journal of Clinical Investigation

Identification of MUP1 as a Regulator for Glucose and Lipid Metabolism in Mice

Yingjiang Zhou, Lin Jiang, Liangyou Rui

Journal of Biological Chemistry

Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases

Jingsong Cao, Yingjiang Zhou, Haibing Peng, +13

Journal of Biological Chemistry

Small Molecule InhibitorsMetabolic DiseasesMetabolic RemodelingInsulin SignalingDgat1 Inhibition +16

SH2B1 Enhances Leptin Signaling by Both Janus Kinase 2 Tyr813 Phosphorylation-Dependent and -Independent Mechanisms

Zhiqin Li, Yingjiang Zhou, Christin Carter‐Su, +2

Molecular Endocrinology