Amanda P. Skoumbourdis

Author

National Institutes of Health

Also Known As

A P Skoumbourdis, Amanda P Skoumbourdis, Amanda P. Skoumbourdis, Amanda Skoumbourdis

Publications

1.9K

Citations

H-Index

Concepts

All Affiliations

National Institutes of Health National Human Genome Research Institute Bristol-Myers Squibb (United States)Pennsylvania State University Dana-Farber Cancer Institute

About

Amanda P. Skoumbourdis is an author at National Institutes of Health specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	396
2	Natural Sciences	6	6	242
3	Biochemistry	5	5	307
4	Biomolecular Engineering	3	3	221
5	Engineering	2	2	190

Amanda P. Skoumbourdis

Publications

1.8K

Citations

H-Index

Page 1

	Year	Citations
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis Dimitrios Anastasiou, Yimin Yu, William J. Israelsen, Nature Chemical Biology	2012	804
A new facile method for the synthesis of 1-arylimidazole-5-carboxylates Bang‐Chi Chen, Mark S. Bednarz, Joseph E. Sundeen, Tetrahedron Letters EngineeringOrganic ChemistrySynthesis MethodSynthetic ChemistryBiomolecular Engineering	2000	178
Evaluation of Substituted <i>N</i>,<i>N</i>′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase Matthew B. Boxer, Jian‐kang Jiang, Matthew G. Vander Heiden, Journal of Medicinal Chemistry	2009	160
Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase Jian‐kang Jiang, Matthew B. Boxer, Matthew G. Vander Heiden, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicinePyruvate KinaseAnti-cancer AgentPharmacology	2010	132
A Virtual Screen for Diverse Ligands: Discovery of Selective G Protein-Coupled Receptor Antagonists Stanislav Engel, Amanda P. Skoumbourdis, John Childress, Journal of the American Chemical Society Drug TargetMedicinal ChemistryVirtual DatabaseVirtual ScreenMolecular Recognition	2008	72
Extending Pummerer Reaction Chemistry. Synthesis of (±)-Dibromophakellstatin by Oxidative Cyclization of an Imidazole Derivative Ken S. Feldman, Amanda P. Skoumbourdis Organic Letters	2005	72
The Inhibition and Treatment of Breast Cancer with Poly (ADP-ribose) Polymerase (PARP-1) Inhibitors Joseph Angel De Soto, Xianyan Wang, Yohei Tominaga, International Journal of Biological Sciences	2006	68
Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors Amanda P. Skoumbourdis, Christopher A. LeClair, Eduard Stefan, Bioorganic & Medicinal Chemistry Letters Pde4 InhibitorsCombinatorial ChemistryMedicinal ChemistrySubstituted TriazolothiadiazinesMedicine	2009	51
Synthesis and Characterization of a BODIPY Conjugate of the BCR-ABL Kinase Inhibitor Tasigna (Nilotinib): Evidence for Transport of Tasigna and Its Fluorescent Derivative by ABC Drug Transporters Suneet Shukla, Amanda P. Skoumbourdis, Martin J. Walsh, Molecular Pharmaceutics Chemoprevention StrategyBodipy Fl TasignaBcr-abl KinaseChemical BiologyFluorescent Derivative	2011	51
Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome Theresa A. Lansdell, Nicole M. Hewlett, Amanda P. Skoumbourdis, Journal of Natural Products	2012	51

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