Amanda P. Skoumbourdis

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis

Dimitrios Anastasiou, Yimin Yu, William J. Israelsen et al. · Nature Chemical Biology · 2012 · 825 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +15

A new facile method for the synthesis of 1-arylimidazole-5-carboxylates

Bang‐Chi Chen, Mark S. Bednarz, Joseph E. Sundeen et al. · Tetrahedron Letters · 2000 · 179 citations

Pharmacy, Chemistry, Medicinal Chemistry +2

Evaluation of Substituted <i>N</i>,<i>N</i>′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase

Matthew B. Boxer, Jian‐kang Jiang, Matthew G. Vander Heiden et al. · Journal of Medicinal Chemistry · 2009 · 164 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase

Jian‐kang Jiang, Matthew B. Boxer, Matthew G. Vander Heiden et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 134 citations

Medicine, Cancer Biology, Pharmacology +4

A Virtual Screen for Diverse Ligands: Discovery of Selective G Protein-Coupled Receptor Antagonists

Stanislav Engel, Amanda P. Skoumbourdis, John Childress et al. · Journal of the American Chemical Society · 2008 · 73 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17