Concepedia

Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase

Jian‐kang Jiang, Matthew B. Boxer, Matthew G. Vander Heiden, Min Shen, Amanda P. Skoumbourdis, Noel Southall, Henrike Veith, William Leister, Christopher P. Austin, Hee Won Park,

Bioorganic & Medicinal Chemistry Letters · 2010 · 134 citations · 28 references

DOI

Concepts

References

28

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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Cancer: Principles and Practice of Oncology.

Annals of Internal Medicine · 1991 · 8.5K citations

, , +10

On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.2K citations

, , +13

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

, , +16

Cancer—Principles & Practice of Oncology

Jonathan E. Rhoads · PubMed Central · 1983 · 1.5K citations · Full text

, , +12