Jian‐kang Jiang - Concepedia

Author

Jian‐kang Jiang

National Institutes of Health

Also Known As

Jian-Kang Jiang, Jian-kang Jiang, Jiankang JIANG, Jiankang Jiang, Jian‐kang Jiang

Publications

5.5K

Citations

H-Index

Concepts

All Affiliations

National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases National Human Genome Research Institute National Center for Advancing Translational Sciences Harvard University

About

Jian‐kang Jiang is an author at National Institutes of Health specializing in medicine, signal transduction, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	11	11	3.1K
2	Biochemistry	7	7	1.7K
3	Natural Sciences	6	6	454
4	Biomolecular Engineering	2	2	57
5	Engineering	1	1	10

Jian‐kang Jiang

Publications

5.2K

Citations

H-Index

Page 1

	Year	Citations
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Cell Metabolism InflammationCytokinePyruvate Kinase M2Signal TransductionSignaling Pathway	2015	1.3K
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses Dimitrios Anastasiou, George Poulogiannis, John M. Asara, Science Lipid PeroxidationCell DeathMetabolic RemodelingRedox BiologyTumor Biology	2011	1.2K
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis Dimitrios Anastasiou, Yimin Yu, William J. Israelsen, Nature Chemical Biology	2012	804
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells Lesley A. Mathews Griner, Rajarshi Guha, Paul Shinn, Proceedings of the National Academy of Sciences	2014	390
Evaluation of Substituted <i>N</i>,<i>N</i>′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase Matthew B. Boxer, Jian‐kang Jiang, Matthew G. Vander Heiden, Journal of Medicinal Chemistry	2009	160
Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion Jianying Feng, Clark Petersen, David H. Coy, Proceedings of the National Academy of Sciences	2010	139
Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase Jian‐kang Jiang, Matthew B. Boxer, Matthew G. Vander Heiden, Bioorganic & Medicinal Chemistry Letters BiochemistryMedicinePyruvate KinaseAnti-cancer AgentPharmacology	2010	132
Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3<i>R</i>,4<i>R</i>)-4-methyl-3-(methyl(7H-pyrrolo[2,3-<i>d</i>]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550) Jian‐kang Jiang, Kamran Ghoreschi, Francesca Deflorian, Journal of Medicinal Chemistry Compounds SelectivityHeterocycle ChemistryChemical BiologyPharmaceutical ChemistryMolecular Pharmacology	2008	124
TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8 <sup>+</sup> T-cell differentiation Ribhu Nayar, Megan Enos, Amanda Prince, Proceedings of the National Academy of Sciences	2012	102
A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism Susanne Neumann, Gunnar Kleinau, Stefano Costanzi, Endocrinology	2008	100

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