Gautam Goel

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

Life Sciences, Immunology, Molecular Medicine +12

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel et al. · Cell Metabolism · 2015 · 1.4K citations · Full text

Life Sciences, Biochemistry, Immunology +16

Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma

Seungmin Hwang, Nicole S. Maloney, Monique W. Bruinsma et al. · Cell Host & Microbe · 2012 · 251 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice From Salmonella Infection

Kara L. Conway, Petric Kuballa, Joo‐Hye Song et al. · Gastroenterology · 2013 · 232 citations

Life Sciences, Immunology, Microbiology +14

Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis

Mélissa Beaudoin, Philippe Goyette, Gabrielle Boucher et al. · PLoS Genetics · 2013 · 217 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17