Gillian M. Tannahill

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

Life Sciences, Immunology, Molecular Medicine +12

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Life Sciences, Endocrinology, Immunology +14

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages

Beth Kelly, Gillian M. Tannahill, Michael P. Murphy et al. · Journal of Biological Chemistry · 2015 · 329 citations · Full text

Life Sciences, Immunology, Pharmacology +16

SOCS2 Can Enhance Interleukin-2 (IL-2) and IL-3 Signaling by Accelerating SOCS3 Degradation

Gillian M. Tannahill, Joanne Elliott, Anna C. Barry et al. · Molecular and Cellular Biology · 2005 · 149 citations · Full text

Life Sciences, Immunology, Molecular Biology +13