Michael P. Murphy

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Edward T. Chouchani, Victoria R. Pell, Edoardo Gaude et al. · Nature · 2014 · 2.8K citations

Life Sciences, Biochemistry, Physiology +16

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills, Beth Kelly, Angela Logan et al. · Cell · 2016 · 2.2K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

Life Sciences, Biochemistry, Cell Biology +12

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen, Jason L. Eriksen, Pritam Das et al. · Nature · 2001 · 1.4K citations

Life Sciences, Neuroscience, Pharmacology +14

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

Geoffrey F. Kelso, Carolyn M. Porteous, Carolyn V. Coulter et al. · Journal of Biological Chemistry · 2001 · 1.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17