Dylan G. Ryan

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills, Beth Kelly, Angela Logan et al. · Cell · 2016 · 2.2K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Evanna L. Mills, Dylan G. Ryan, Hiran A. Prag et al. · Nature · 2018 · 1.8K citations

Life Sciences, Biochemistry, Cell Biology +12

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

James O. Early, Deepthi Menon, Cathy Wyse et al. · Proceedings of the National Academy of Sciences · 2018 · 369 citations · Full text

Life Sciences, Immunology, Physiology +17

Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming

David Olagnier, Aske M. Brandtoft, Camilla Gunderstofte et al. · Nature Communications · 2018 · 286 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

High-dimensional single-cell analysis of human natural killer cell heterogeneity

Lucas Rebuffet, Janine Melsen, Bertrand Escalière et al. · Nature Immunology · 2024 · 228 citations · Full text

Life Sciences, Cell Biology, Immunology +15