Beth Kelly

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

Life Sciences, Immunology, Molecular Medicine +12

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills, Beth Kelly, Angela Logan et al. · Cell · 2016 · 2.2K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

Daniel J. Puleston, Michael D. Buck, Ramon I. Klein Geltink et al. · Cell Metabolism · 2019 · 404 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages

Beth Kelly, Gillian M. Tannahill, Michael P. Murphy et al. · Journal of Biological Chemistry · 2015 · 329 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

Stefano Angiari, Marah C. Runtsch, Caroline E. Sutton et al. · Cell Metabolism · 2019 · 319 citations · Full text

Life Sciences, Biochemistry, Immunology +17